Hasil pencarian

Prosiding Workshop dan Seminar Nasional Farmasi Universitas Udayana

Dokumen pengajaran Teori Manajemen Farmasi 4A

Dokumen pengajaran teori Manajemen Farmasi 4B

Metopen B

Metopen A

Pengaruh Perbedaan Metode Ekstraksi Terhadap Rendemen dan Kandungan Kimia Ekstrak Daun Katuk (Sauropus androgynus)

Katuk leaves contain chemical compounds such as alkaloids, tannins, flavonoids, saponins and steroids. Extraction of a plant can affect the yield and chemical content. The purpose of this study was to determine the effect of different extraction methods on the yield and chemical content of katuk leaf extract. This research method uses Post-test Only Design and the extraction used is maceration and soxhlet, with 96% ethanol solvent. 50 g of simplisia powder was macerated with solvent in a ratio of 1:10 for 3x24 hours. Soxhlet extraction is carried out until the liquid is no longer colored. The filtrate obtained was evaporated and air dried until a thick extract was obtained. The extracts obtained from each extraction method were calculated for yield and chemical content. The yield was calculated statistically with the Shapiro-Wilk normality test. If the data is normal and homogeneous , the Independent Sample T-Test test is continued, if the data is not normal and not homogeneous, the Mann-Whitney test is continued. While the chemical content is descriptive.

Tingkat Pengetahuan Ibu tentang Penggunaan Obat Cacing di Puskesmas Umbulharjo II Yogyakarta

Helminthiasis is caused by poor hygiene and sanitation, non-adherence to deworming treatment, and lack of knowledge about worm infections. Cases of helminthiasis infection in Yogyakarta Special Region (DIY) in 2015 reached 182 cases and in 2016 reached 165 cases. This study took place at Umbulharjo II Community Health Center in Yogyakarta. The purpose of this study was to determine the level of maternal knowledge about the use of deworming drugs at Puskesmas Umbulharjo II Yogyakarta. This study is a descriptive type of observational research. Prospective data collection with sampling using purposive sampling method. Data were collected using a questionnaire instrument and analyzed by calculating the percentage value of correct answers to filling out the questionnaire then the level of knowledge was categorized as good, sufficient, lacking. The number of samples used in this study was 90 people.

Tingkat Pengetahuan Pasien Terhadap Penanganan Diare Pada Anak di Apotek Kaliurang Sedayu Bulan Februari - Maret 2024

Diarrhea is one of the infectious diseases of the digestive tract which is a health problem in the world including Indonesia. The incidence of diarrhea increased by about 2 billion incidence of diarrhea and 1.9 million resulted in deaths in children under five worldwide. The prevalence rate of childhood diarrhea in Indonesia was recorded as 18,665 (9%) children aged 0-11 months, 18,333 (15%) children aged 12-23 months, 19. 112 (12.8%) children aged 24-35 months, 18,821 (10.2%) children aged 36-47 months and as many as 18,688 (8%) children aged 48-59 months.The purpose of this study was to determine the level of parental knowledge of the treatment of diarrhea in children at Kaliurang Sedayu Pharmacy. This study used descriptive observational method. This study used quantitative data to determine the level of parental knowledge on the treatment of diarrhea in children at Kaliurang Sedayu Pharmacy. Data analysis used a Guttman scale where the correct answer was given a score of 1 and the wrong answer was given a score of 0.

Pengaruh Jenis Pelarut Terhadap Rendemen dan Kandungan Kimia Ekstrak Daun Katuk (Sauropus androgynus)

Katuk leaves contain chemical compounds such as alkaloids, tannins, flavonoids, saponins, triterpenoids, polyphenols, steroids, quinones, monoterpenoids and sesquiterpenoids. Factors that influence the yield and chemical content of katuk leaf extract are differences in the type of solvent. The aim of this research was to determine the effect of the type of extraction solvent on the yield value and chemical content of katuk leaf extract. The extraction method used in this research was maceration, using 96% ethanol and n-hexane as solvents. Simplicia powder is macerated with each solvent (ratio 1:3) for 3 x 24 hours with stirring 15 minutes every 24 hours. The maceration results obtained were then filtered and air dried until a thick extract was obtained, then the yield value and chemical content of the katuk leaf extract were tested. Data from the results were analyzed using SPSS with the Shapiro Wilk normality test and Levene's homogeneity test with a confidence level of 95%. The yield value data was then subjected to an Independent Sample T-test to determine the influence between groups of solvent types.

AKTIVITAS ANTIOKSIDAN DAN UJI IRITASI KRIM EKSTRAK ETANOL DAUN KETAPANG

Uji Viskositas dan Diameter Sebar Sediaan Gel Sari Buah Strawberry (Fragaria x ananssa Duch.) dengan Basis CMC Na

Strawberry is a fruit that contains antioxidant compounds that are effective for maintaining skin health and preventing premature aging. To facilitate its application, strawberry juice is formulated in gel form. The gel is formulated with CMC Na (Carboxymethyl cellulose Sodium) base. CMC Na has good attachment strength to the skin and can also increase the viscosity of gel preparations. This study aims to determine the effect of the addition of strawberry juice on the viscosity and diameter of spread of CMC Na-based gel preparations. This study was conducted using an experimental method, namely post testonly control group design by making the preparation formula, namely gel formula without strawberry juice (F1) and gel formula with strawberry juice (F2). Gel is made by developing CMC Na in water heated at a temperature of 80°C until it forms like a gel, then covered with aluminium and left to stand for 24 hours.The gel was allowed to stand for 24 hours so that the gel preparation could expand properly. The preparation was evaluated by viscosity and diameter spread test. Data that were normally distributed were analysed using the Independent t-test and data that were not normally distributed were tested with the Mann withney test with 95% confidence level.

Pengaruh Konsentrasi Sari Buah Jambu Biji Merah (Psidium guajava Linn.) Terhadap Nilai pH Sediaan Lip Balm

Lip balm merupakan pelembab bibir yang dikemas dalam bentuk semi padat. Salah satu bahan alami yang dapat digunakan untuk pembuatan sediaan lip balm yaitu buah jambu biji merah karena kandungan vitamin C yang tinggi. Derajat keasaman (pH) merupakan parameter penting dalam produk kosmetik yang dapat mempengaruhi tingkat daya penyerapan pada kulit. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi sari buah jambu biji merah terhadap nilai pH sediaan lip balm. Jenis penelitian ini adalah eksperimental dengan metode posttest only control grup design. Formula lip balm terdiri dari formula kontrol basis dan formula dengan sari buah jambu biji merah 2,5% (FI), 5% (FII) dan 7,5% (FIII). Sediaan lip balm yang masing- masing telah di uji pH menggunakan pH meter digital. Analisis data penelitian dilakukan menggunakan program SPSS 23. Uji normalitas dilakukan dengan Shapiro-Wilk dan uji homogenitas dilakukan dengan Levene’s Test. Jika data yang dihasilkan, yaitu data terdistribusi normal dan homogen dilanjutkan dengan uji One Way Anova. Jika nilai yaitu P0,05 maka dilanjutkan dengan Uji LSD. Namun jika data tidak terdistribusi normal dilakukan uji non parametrik dengan Kruskall Wallis.

Gambaran Tingkat Pengetahuan tentang DAGUSIBU Obat pada Masyarakat Dusun Pereng Kabupaten Kulon Progo Periode Januari - Fabruari 2024

Drug abuse is a problem that often occurs in the community. DAGUSIBU is a program to realize a drug-aware family movement. The level of knowledge of DAGUSIBU medicine among PKK mothers in Panjang Kidul neighborhood, Semarang Regency is still in the insufficient category, which is 59%. The purpose of the study was to determine the description of the level of knowledge about DAGUSIBU medicine in the community of Pereng Hamlet, Kulon Progo Regency. This study uses an observational method that is descriptive in nature. Sampling by purposive sampling based on inclusion and exclusion criteria in 137 respondents. The research instrument used was a closed questionnaire. Data analysis was carried out by summing up the scores of each respondent, then calculating the percentage of the assessment to determine the level of community knowledge included in the good, sufficient, or lacking category.

Pengaruh Konsentrasi Pelarut Terhadap Kandungan Kimia dan Nilai Rendemen Ekstrak Daun Pandan Wangi (Pandanus amarillyfolius Roxb.)

Pandan wangi leaf extract contains alkaloid, flavonoid, tannin, and saponin compounds. The withdrawal of these compounds is carried out using a maceration extraction process with variations in solvent concentration. The variation of solvent concentration can affect the chemical content and yield value. This study aims to determine the effect of solvent concentration on the chemical content and yield value of pandan wangi leaf extract in 70% ethanol and 96% ethanol solvents. Post-test Only Design experimental research method by extracting by maceration of fragrant pandanus leaves using 70% ethanol and 96% ethanol solvents. The results of each extraction were calculated and chemical content tests were carried out, namely, phenolic, flavonoid, alkaloid, tannin, saponin, steroid and terpenoid tests. The results of chemical content were tested descriptively, while the results of the yield value were analyzed with SPSS. The normality test was performed using the Shapiro-Wilk test because the sample tested was 50 and the homogeneity test was performed using the Levence test. Then further tests were carried out using the Independent Sample T-Test test. Translated with DeepL.com (free version)

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Terhadap Bakteri Staphylococcus epidermidis

Kersen leaves has known to have antibacterial activity. This study aims to determine the antibacterial activity of kersen leaves ethanol extract against S. epidermidis bacteria and to determine the potential activity against S. epidermidis bacteria compared to gentamicin. Kersen leaves were extracted by maceration with 96% ethanol solvent for 24 hours. Tests were carried out using the well-diffusion method using 7 treatment groups, kersen leaves ethanol extract concentrations of 25%, 50%, 75%, 100% as test sample, gentamicin concentration of 10µg as a positive control, aqua pro injection as a negative control, and 96% ethanol as a solvent control. Each treatment was incubate at 35oC for 24 hours. The data obtained in the form of inhibition zones were and analyzed and measure for sensitivity based on CLSI. Antibacterial activity indicates the diameter of inhibition zone of bacteria S. epidermidis in concentration 25%, 50%, 75%, and 100% respectively of 11,46±0,15mm; 9,26±0,20mm; 7,80±0,10mm dan 6,30±0,20mm with the category of resistnace and gentamicin showed the diameter of inhibition zone was 12,06±0,11mm with a resistanc category. The conclusion of the study, kersen leaves extract has antibacterial activity against S. epidermidis bacteria, but its potency is not comparable to gentamicin in inhibiting the growth of S. epidermidis

Uji Sifat Fisikokimia Sediaan Lipstik Ekstrak Angkak Merah (Monascus purpureus)

Angkak merupakan beras hasil fermentasi oleh kapang (Monascus purpureus) sehingga berwarna merah,yang dapat digunakan untuk membuat pewarna bibir yang memiliki antioksidan. Lipstik salah satu sediaan kosmetik yang paling banyak digunakan untuk pewarna bibir, dilengkapi dengan elemen untuk menghidrasi dan melindungi bibir. Tujuan dari penelitian ini Untuk mengetahui perbedaan variasi konsentrasi cera alba dapat memenuhi persyaratan uji fisikokimia dari sediaan lipstik ekstrak angkak. Penelitian ini menggunakan metode penelitian eksperimental post test only design. Ekstraksi angkak menggunakan metode maserasi dengan pelarut etanol 96%. Ekstrak angkak dibuat dalam sediaan lipstik basis cera alba dengan variasi konsentrasi 10%, 15% dan 20%. Pengujian organoleptis dan homogenitas dianalisis secara deskriptif sedangkan hasil pH dan hasil titik lebur dianalisis menggunakan program IBM SPSS Statistik 23. Langkah awal uji normalitas Shapiro Wilk dan uji homogenitas dengan uji Levene’s test, jika data terdistribusi normal dan homogen (sig > 0,05) dilanjutkan dengan uji One Way Anova. Jika pada uji One Way Anova terdapat perbedaan bermakna (sig < 0,05) maka dilakukan uji lanjutan dengan uji LSD. Jika data tidak terdistribusi normal dilakukan uji Kruskal Wallis, jika pada uji Kruskal Wallis terdapat perbedaan bermakna (sig < 0,05) maka dilakukan uji lanjutan dengan uji Mann Whitney.

Uji Sifat Fisikokimia Sediaan Lipbalm Ekstrak Angkak Merah (Monascus purpureus)

Lipbalm merupakan sediaan yang digunakan pada bibir bertujuan untuk melindungi bibir dari pengaruh buruk lingkungan. Selain dapat melindungi bibir lipbalm juga dapat memberikan warna pada bibir. Angkak merupakan beras hasil fermentasi kapang Monascus purpureus yang dapat memberikan pigmen warna merah. Tujuan dari penelitian ini adalah memformulasikan ekstrak angkak (Monascus purpureus) menjadi sediaan lipbalm. Penelitian ini menggunakan metode penelitian eksprimental posttest only design. Ekstrak angkak diperoleh dengan cara maserasi dengan pelarut etanol 96% selama 1x24 jam kemudian di remaserasi sebanyak 2 kali. Cera flava diformulasikan dengan variasi konsentrasi 10%, 15%, 20%. Hasil pengujian organoleptis dan homogenitas dianalisis secara deskriptif sedangkan hasil pH dan hasil titik lebur dianalisis dengan program IBM SPSS Statistik 23. Uji normalitas dilakukan dengan uji Shapiro Wilk dan uji homogenitas dilakukan dengan uji Levene’s test, jika nilai (sig >0,05) maka data terdistribusi normal dan homogen selanjutnya dilanjutkan dengan uji One Way Anova. Jika pada uji One Way Anova terdapat perbedaan bermakna (sig <0,05) maka dilanjutkan dengan uji LSD. Jika data terdistribusi normal dilanjutkan dengan uji Kruskal Walis, selanjutnya jika terdapat perbdaan bermagna (sig <0,05) maka dilanjutkan dengan uji Mann Whitney.

Gambaran Tingkat Pengetahuan Penggunaan Obat Bebas dan Obat Bebas Terbatas untuk Swamedikasi Pada Masyarakat Desa Keloran Bantul Februari 2024

Self-medication is an action that is most often done by someone before finally deciding to see a doctor. Self-medication is done to treat minor illnesses. Self-medication is usually done with over-the-counter drugs and limited over-the-counter drugs that can be obtained at stalls, drug stores, and pharmacies. Research conducted in Sijunjung Regency regarding the use of over-the-counter drugs and limited over-the-counter drugs for self-medication resulted in 12% in the good category, 33% in the sufficient category, and 55% in the deficient category. This study aims to determine the level of knowledge of Keloran Village residents regarding the use of over-the-counter drugs and limited over-the-counter drugs in February 2024. This research is a descriptive observational study. The sample used was 100 people taken by purposive sampling method. Data analysis begins with validity and reliability tests. The level of knowledge was assessed based on the score, namely the correct answer was given a score of 1 and the wrong answer was given a value of 0. The data obtained from the questionnaire was then calculated by calculating the percentage of knowledge level assessment. The percentage results were categorized into good, sufficient, and deficient categories. Keywords: Knowledge level, self-medication, over-the-counter drugs, limited over-the-counter drugs

Uji pH dan Diameter Sebar Sediaan Gel Ekstrak Daun Pepaya (Carica papaya L.) Dengan Basis Karbopol

Papaya leaves contain carpine alkaloid compounds which function as antibacterial and anti-acne. Papaya leaves can be made in extract form used as an active ingredient in gel preparations. Gel base used using carbopol. Carbopol was chosen because it is non-toxic and not irritates the skin when used topically. It is non-toxic and notirritates the skin when used topically. Gel preparation needs to be done test evaluation. This research aims to determine the effect of addition papaya leaf extract against pH test and distribution diameter test.

Pengaruh Konsentrasi Natrium Hidroksida Terhadap Kadar Air Sediaan Sabun Padat Daun Pepaya (Carica Papaya L.)

Papaya leaves contain antibacterial compounds such as tannins, flavonoids, terpenoids and saponins which function as antiseptics. Based on its activity, papaya leaves can be used as an antiseptic to form solid soap. Solid soap is a cleanser made by chemically reacting sodium base and fatty acids. NaOH is the main ingredient in the saponification process. This research aims to determine the effect of NaOH concentration on the water content of papaya leaf solid soap preparations. This research is an experimental Post-test Only Design research. Variations in NaOH concentration used were 5%; 8.5%; and 12%. The research carried out included making solid soap preparations and testing water content. Data analysis used the SPSS 26 program. Data was tested for normality using the Shapiro – Wilk method. If the data is normally distributed and homogeneous then proceed with the One Way ANOVA test with a confidence level of 95%. If the Sig value is 0.05 then proceed with the Post Hoc LSD test. The water content test results obtained on FI, FII and FIII respectively were 5.4 ± 0.1%; 4.43±01%; and 3.4 ± 0.1%. The results of the Post Hoc LSD test obtained a significant value of 0.000 0.05, which means there is a significant difference in variations in NaOH concentration. The conclusion of this research is that variations in the concentration of NaOH in the solid papaya leaf soap used have an effect on the water content of the solid papaya leaf soap preparation.