ThesisOpen AccessMetadata saja
2025•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Hipertensi merupakan suatu peningkatan tekanan darah sistolik ≥140 mmHg dan tekanan darah diastolik ≥90 mmHg. Pisang ambon memiliki kandungan kalium yang tinggi sehingga baik untuk menjaga tekanan darah tetap stabil. Kalium memiliki efek diuretik yang dapat menurunkan tekanan darah dengan meningkatkan pengeluaran natrium dan air melalui urin. Penelitian ini bertujuan untuk mengetahui efek diuretik pisang ambon pada tikus putih jantan galur wistar.
Penelitian ini menggunakan metode eksperimental dengan desain penelitian post test only control group design. Sebanyak 27 ekor tikus putih jantan galur wistar dibagi menjadi tiga kelompok yaitu kelompok kontrol negatif (CMC Na), kelompok kontrol positif (furosemide), dan kelompok perlakuan (pisang ambon). Pengujian efektivitas diuretik dilakukan dengan melihat volume urin dari ketiga kelompok tiap 1 jam selama 6 jam. Hasil volume urin dianalisis menggunakan Kruskal Wallis IBM SPSS Statistics versi 26 dengan taraf kepercayaan 95%.
Hasil rerata volume urin selama 6 jam pada kelompok I, II, dan III secara berturut-turut yaitu 4,308 ml; 37,987 ml; dan 22,059 ml. Kesimpulan pada penelitian ini adalah pisang ambon memiliki efektivitas sebagai diuretik pada tikus putih jantan galur wistar dengan pemberian pisang ambon seberat 17,599 g, namun efektivitas diuretik yang dihasilkan pisang ambon tidak sekuat furosemide yang merupakan loop diuretic.
Hypertension is an increase in systolic blood pressure ≥140 mmHg and diastolic blood pressure ≥90 mmHg. Ambon banana has a high potassium content so that is good for keeping blood pressure stable. Potassium has a diuretic effect that can lower blood pressure by increasing the excretion of sodium and water through urine. This study aims to determine the diuretic effect of ambon banana on male white rats wistar strain.
This study used an experimental method with a post test only control group design. A total of 27 male white rats wistar strain were divided into three groups: negative control group (CMC Na), positive control group (furosemide), and treatment group (ambon banana). Testing the effectiveness of diuretics was carried out by looking at the urine volume of the three groups every 1 hour for 6 hours. Urine volume results were analyzed using Kruskal Wallis IBM SPSS Statistics version 26 with 95% confidence level.
The average urine volume for 6 hours in groups I, II, and III were 4,308 ml; 37,987 ml; and 22,059 ml, respectively. The conclusion of this study is that ambon banana has effectiveness as a diuretic in male white rats wistar strain by giving 17,599 g of ambon banana, but the diuretic effectiveness of ambon banana is not as strong as furosemide which is a loop diuretic.
ThesisOpen AccessMetadata saja
2024•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Hypertension is one of the most common diseases found in Indonesia. More than 63 million Indonesians suffer from hypertension with a death rate of more than 427 people. Based on a survey at the Kasihan II Community Health Center, hypertension cases were ranked first among the top ten diseases. This research was conducted to determine the pattern of antihypertensive drug prescribing at the Kasihan II Community Health Center in December 2023.
This research used a descriptive observational method. Retrospective data collection used medical record data and prescriptions from hypertensive patients in December 2023. Data was analyzed quantitatively by describing and calculating percentages including patient characteristics, type of hypertension therapy, antihypertensive drug class, comorbidities and antihypertensive drug dosage. The results of the data percentage are presented in table form.
ThesisOpen AccessMetadata saja
2024•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Hypertension is still one of the diseases whose prevalence has increased and is estimated to reach 29.2% in year 2025. In previous studies related to the pattern of use of antihypertensive drugs, the most widely used single antihypertensive drug is amlodipine, while the combination antihypertensive drugs used are amlodipine and candesartan. The combination used was amlodipine and candesartan. Objective This study aims to determine the pattern of use of hypertension drugs at Bethesda Lempuyangwangi Hospital Yogyakarta during May to July 2023. The research methodology used is an observational method that is methodology used was descriptive observational method by taking data from prescriptions and medical records retrospectively in records retrospectively from May 2023 to July 2023. Data were analysed quantitatively, namely by describing and calculating the percentage of each drug and drug class and type of therapy. percentage of each drug and the most widely used drug class and type of therapy. Then the data will be presented in tabular form.
ThesisOpen AccessMetadata saja
2023•Skripsi, Thesis, Disertasi, dan Tugas Akhir
The prevalence of hypertension in Sleman district in 2018 was ranked third with a percentage of 32.01% in the province of DIY. This research took place at the Gamping 1 Health Center in Sleman Yogyakarta that hypertension is number 1 out of the top 10 diseases in 2022 with 2,115 cases. Evaluation of the use of antihypertensive drugs aims to ensure that the correct and effective use of drugs in hypertensive patients, the correct and effective use of drugs is very important for evaluating the use of hypertension drugs at the Gamping 1 Public Health Center, Sleman, Yogyakarta for the period July - December 2022. This study used the method observational research which is analytic in nature with retrospective data collection and the sampling technique is simple random sampling. The data that was examined used prescription data and medical records of hypertension patients at the Gamping 1 Health Center in July - December 2022 as many as 336 samples. The data obtained is then evaluated for its rationale by calculating the percentage of the right indication, the right patient, the right drug, and the right dose.
ThesisOpen AccessMetadata saja
2023•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Hipertensi merupakan penyakit dimana tekanan darah sistolik ≥ mmHg dan atau tekanan darah diastolik ≥ 90 mmHg. Berdasarkan studi pendahuluan oleh peneliti di Puskesmas Purwosari hipertensi menjadi peringkat pertama dari sepuluh besar penyakit. Penanganan obat antihipertensi dengan terapi farmakologi yang tepat merupakan salah satu langkah strategis penanganan hipertensi. Tujuan penelitian ini untuk mengetahui gambaran peresepan obat antihipertensi pada pasien hipertensi di Puskesmas Purwosari Kabupaten Gunungkidul periode Januari – Juni 2022.
Penelitian ini menggunakan metode observasional yang bersifat deskriptif dengan pengumpulan data secara retrospektif. Pengambilan data dengan metode random sampling dengan jumlah rekam medis sebanyak 91. Data dianalisis secara deskriptif kemudian hasil data disajikan dengan persentase dalam bentuk tabel atau diagram. Hasil peneltian berupa distribusi data berdasarkan karakteriktik pasien, nama dan golongan obat, serta jenis terapi.
