ThesisOpen AccessMetadata saja
2025•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Diabetes mellitus is a chronic disease caused by the pancreas's inability to produce enough insulin or effectively use the insulin produced. The prevalence of diabetes mellitus in Indonesia reaches 8.5%, with about 90% of those cases being type 2 diabetes mellitus. Oral antidiabetic therapy is the primary choice for treating type 2 diabetes. The success of this therapy can be assessed through HbA1c levels, which reflect long-term blood sugar control. This study aims to determine the effect of different types of oral antidiabetic therapy on HbA1c levels in patients with type II diabetes mellitus at Puskesmas Pleret. The research method uses an observational analytic design with a retrospective approach based on the medical records data of patients with type 2 diabetes mellitus. The population in this study consists of all medical records of prolanis patients diagnosed with type 2 diabetes mellitus at Puskesmas Pleret in May 2025. Sampling was done using saturated sampling technique on 65 medical records. Data analysis included patient characteristics, use of oral antidiabetic agents, achievement of HbA1c, and the effect of oral antidiabetic agents on HbA1c using Chi-Square, in SPSS version 25 to determine the effect of the type of antidiabetic medication on HbA1c levels. The results of this study's Chi-Square test showed a significance value (2-sided) of 0.691 > 0.05. This means that there is no effect of the type of therapy on HbA1c levels in prolanis type II diabetes patients.
ThesisOpen AccessMetadata saja
2024•Skripsi, Thesis, Disertasi, dan Tugas Akhir
The Special Region of Yogyakarta is ranked first with the highest number of diabetes mellitus patients at 2.6%. Treatment that is not immediately carried out in patients with diabetes mellitus can cause complications, including hypertension. The Special Region of Yogyakarta has a prevalence of diabetes mellitus with hypertension of 68%, which is followed by an increase in the use of various drugs, causing drug interactions that can affect the patient's condition. This study aims to determine the potential interaction of oral antidiabetic drugs with antihypertensive drugs.
This study used an observational method that was analytical in nature, with retrospective data collection on BPJS patient prescriptions at Medikatama Yogyakarta Pharmacy for the period October 1–December 31, 2023. Sampling using the purposive sampling technique on 100 BPJS patient prescription data. Data analysis includes patient characteristics (name, age, and gender) and potential interactions (interaction occurrence, interacting drugs, and severity) based on Medscape.
Keywords: antidiabetics, antihypertensives, drug interactions
ThesisOpen AccessMetadata saja
2024•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Prevalensi Diabetes Melitus (DM) di Indonesia diperkirakan akan mengalami lonjakan sekitar 21,3 juta pada tahun 2030 dan sebanyak 90% dari kasus DM di dunia adalah DM tipe 2. Pengobatan DM tipe 2 dirasa penting untuk mencegah terjadinya komplikasi. Salah satu terapi pengobatan DM tipe 2 yaitu dengan Obat Antidiabetik Oral. Penelitian ini bertujuan untuk mengetahui pola penggunaan antidiabetik oral pada pasien DM tipe 2 di Rumah Sakit PKU Muhammadiyah Yogyakarta Tahun 2023.
Metode penelitian yang digunakan adalah observasional bersifat deskriptif dengan pengambilan data secara retrospektif pada data rekam medis pasien DM tipe 2. Populasi pada penelitian ini yaitu seluruh rekam medis pasien dengan diagnosa DM tipe 2 rawat jalan di RS PKU Muhammadiyah Yogyakarta Tahun 2023. Pengambilan sampel dengan teknik purposive sampling pada 624 rekam medis dan Analisa data meliputi karakteristik pasien (jenis kelamin, usia) dan pola penggunaan antidiabetik oral (jenis terapi, jenis obat, golongan obat).
ThesisOpen AccessMetadata saja
2023•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Diabetes mellitus is a chronic disease characterized by high blood sugar levels due to impaired insulin secretion. The prevalence of diabetes mellitus based on a doctor's diagnosis in residents aged ≥ 15 years in the Special Region of Yogyakarta in 2018 was 3.1%. This study aims to determine the pattern of prescribing antidiabetic drugs in patients with type 2 diabetes mellitus at the Tegalrejo Health Center Yogyakarta including patient characteristics, type of antidiabetic, antidiabetic class, and dosage suitability based on Perkeni 2021. This research is an analytic observational study with retrospective data collection on prescriptions for type 2 diabetes mellitus patients in October-November 2022 at the Tegalrejo Health Center, Yogyakarta. The sample in this study was 85 recipes, using a purposive sampling technique. Data analysis was carried out using quantitative data, the data will be displayed in the form of tables. The results and conclusions in the study at the Tegalrejo Health Center in Yogyakarta were that the characteristics of type 2 diabetes mellitus patients were mostly women (77.7%) with the most age > 65 years (47.1%). The most frequent diagnosis of type 2 diabetes mellitus patients with comorbidities was 84.7%. The most widely used antidiabetic is Metformin (66.4%) which is a biguanide group. The appropriate dose for anti-diabetic drugs is 100% correct according to the Perkeni 2021.
