ThesisOpen AccessMetadata saja
2026•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Buah okra (Abelmoschus esculentus L.) mengandung senyawa bioaktif
seperti fenolik, alkaloid, dan terpenoid yang berkhasiat sebagai antidiabetik dan
gastroprotektor. Masyarakat umum mengonsumsi okra dalam bentuk infusa
maupun sari. Perbedaan suhu dan proses metode pengolahan sari dan infusa
berpotensi mempengaruhi jenis senyawa yang tersari. Penelitian ini bertujuan
membandingkan hasil skrining fitokimia antara infusa dan sari buah okra untuk
menentukan metode pengolahan yang paling tepat dalam mempertahankan
senyawa bioaktif.
Penelitian ini dilakukan secara eksperimental Post-test only design. Buah
okra segar dicuci bersih dan diolah menjadi 2 jenis sediaan, yaitu infusa dan sari.
Pembuatan infusa dilakukan dengan cara merebus buah pada suhu 90°C selama 15
menit, sedangkan Pembuatan sari buah dilakukan dengan menghancurkan buah
bersama air dengan blender, kemudian disaring untuk diambil sarinya. Uji fitokimia
dilakukan pada masing-masing sediaan meliputi uji fenolik, flavonoid, alkaloid,
saponin, tanin, dan terpenoid. Pengujian dilakukan dalam 3 kali pengulangan, data
disajikan dan dibandingkan secara deskriptif dalam bentuk tabel.
Hasil skrining fitokimia menunjukan bahwa sediaan infusa buah okra positif
senyawa fenolik dan flavonoid, sedangkan sediaan sari buah okra menunjukan
positif senyawa fenolik, flavonoid, dan alkaloid. Kesimpulan dari penelitian ini
menunujukan terdapat perbedaan hasil skrining fitokimia infusa dan sari buah okra.
ThesisOpen AccessMetadata saja
2025•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Kenikir leaves (Cosmos caudatus Kunth.) are tropical plants that are known to contain secondary metabolite compounds such as flavonoids, phenolics, alkaloids, saponins, and others. The traditional use of kenikir leaves encourages the need for scientific research to determine its bioactive content more specifically based on its form. This study aims to compare the content of active compounds between the juice and decoction of kenikir leaves with a qualitative phytochemical screening test.
The research was conducted experimentally using a post-test only design. Kenikir leaves are obtained from independent plants that are cultivated organically, then harvested in fresh conditions, washed clean, and processed into two forms of preparations, namely juice and decoction of kenikir leaves. Both preparations are then subjected to phytochemical screening that identifies the content of bioactive compounds. The tests included seven groups of compounds: phenolics, flavonoids, alkaloids, tannins, saponins, as well as steroids and triterpenoids. Each test was carried out in three iterations, and the data were presented in the form of a table to be descriptively compared with previous studies.
The results showed that the preparation of kenikir leaf juice was positive for phenolic compounds, flavonoids, and alkaloids, while the preparation of the kenikir leaf decoction was positive for phenolic compounds, flavonoids, alkaloids, and saponins. The conclusion of this study shows that there is a difference in the results of phytochemical screening of cider and kenikar leaf stew.
ThesisOpen AccessMetadata saja
2025•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Buah mengkudu mengandung senyawa seperti flavonoid, alkaloid, saponin, antrakuinon dan triterpenoid yang dapat diketahui melalui proses uji skrining fitokimia. Perbedaan metode penyarian dapat mempengaruhi senyawa aktif yang diperoleh pada suatu sampel. Faktor yang perlu diperhatikan dalam proses pengambilan senyawa, seperti adanya perbedaan suhu dan ukuran partikel. Tujuan penelitian ini adalah untuk mengetahui perbedaan hasil skrining fitokimia sari dan rebusan buah mengkudu. Penelitian ini merupakan penelitian eksperimental post-test only design. Buah mengkudu dibuat dalam dua sampel yaitu sari dan rebusan dengan perbandingan buah mengkudu sebanyak 100 g dengan air sebanyak 100 ml. Sampel kemudian diuji skrining fitokimia meliputi uji polifenol, flavonoid, saponin, tannin, terpenoid dan alkaloid. Pengujian dilakukan sebanyak 3 kali replikasi. Hasil data kemudian disajikan dalam bentuk tabel yang terdiri dari pengujian, reagen dan keterangan. Hasil uji yang diperoleh dibandingkan dengan hasil penelitian terdahulu. Hasil uji skrining fitokimia pada buah mengkudu menggunakan metode sari positif mengandung senyawa fenolik, saponin, tanin dan alkaloid tetapi tidak mengandung senyawa flavonoid, terpenoid dan steroid, sedangkan pada rebusan tidak menunjukan adanya senyawa fenolik, flavonoid, tanin, alkaloid, terpenoid dan steroid namun positif mengandung senyawa saponin. Kesimpulan pada penelitian ini menunjukkan bahwa terdapat perbedaan hasil uji skrining sari dan rebusan buah mengkudu.
ThesisOpen AccessMetadata saja
2024•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Strawberry is a fruit that contains antioxidant compounds that are effective for maintaining skin health and preventing premature aging. To facilitate its application, strawberry juice is formulated in gel form. The gel is formulated with CMC Na (Carboxymethyl cellulose Sodium) base. CMC Na has good attachment strength to the skin and can also increase the viscosity of gel preparations. This study aims to determine the effect of the addition of strawberry juice on the viscosity and diameter of spread of CMC Na-based gel preparations. This study was conducted using an experimental method, namely post testonly control group design by making the preparation formula, namely gel formula without strawberry juice (F1) and gel formula with strawberry juice (F2). Gel is made by developing CMC Na in water heated at a temperature of 80°C until it forms like a gel, then covered with aluminium and left to stand for 24 hours.The gel was allowed to stand for 24 hours so that the gel preparation could expand properly. The preparation was evaluated by viscosity and diameter spread test. Data that were normally distributed were analysed using the Independent t-test and data that were not normally distributed were tested with the Mann withney test with 95% confidence level.
ThesisOpen AccessMetadata saja
2023•Skripsi, Thesis, Disertasi, dan Tugas Akhir
The chemical compounds found in avocado leaves include alkaloids, triterpenoids, steroids, tannins and flavonoids. Good chemical content can be obtained by paying attention to the quality and quality of simplicia. Good simplicia is obtained through the process of specific and non-specific standardization. One of the specific standardization is water soluble essence content and ethanol soluble essence content. The purpose of this study was to determine the water soluble extract content and ethanol soluble extract content found in avocado leaf simplicia.
The method used in this study is an experimental posttest only design. Avocado leaf simplicia was dried by wind drying method at 25°-26°C for 7 days. Avocado leaf powder was tested for water soluble extract content and ethanol soluble extract content using the gravimetric method. Data analysis was carried out descriptively and compared with the Indonesian Herbal Pharmacopoeia Edition II.
The results of the avocado leaf simplicia study showed that the average ethanol-soluble extract content was 8.15% ± 14.6%, the ethanol-soluble extract content was 14.33% ± 135%. The results of this analysis showed that the compounds contained in the avocado leaf simplicia were higher Most contain non-polar compounds.
The conclusion of this study was that the ethanol soluble extract of avocado leaf simplicia met the standard requirements of the Indonesian Herbal Pharmacopoeia Edition II of not less than 13.5%.
ThesisOpen AccessMetadata saja
2023•Skripsi, Thesis, Disertasi, dan Tugas Akhir
Hipertensi merupakan penyakit dimana tekanan darah sistolik ≥ mmHg dan atau tekanan darah diastolik ≥ 90 mmHg. Berdasarkan studi pendahuluan oleh peneliti di Puskesmas Purwosari hipertensi menjadi peringkat pertama dari sepuluh besar penyakit. Penanganan obat antihipertensi dengan terapi farmakologi yang tepat merupakan salah satu langkah strategis penanganan hipertensi. Tujuan penelitian ini untuk mengetahui gambaran peresepan obat antihipertensi pada pasien hipertensi di Puskesmas Purwosari Kabupaten Gunungkidul periode Januari – Juni 2022.
Penelitian ini menggunakan metode observasional yang bersifat deskriptif dengan pengumpulan data secara retrospektif. Pengambilan data dengan metode random sampling dengan jumlah rekam medis sebanyak 91. Data dianalisis secara deskriptif kemudian hasil data disajikan dengan persentase dalam bentuk tabel atau diagram. Hasil peneltian berupa distribusi data berdasarkan karakteriktik pasien, nama dan golongan obat, serta jenis terapi.
