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Gambaran Tingkat Pengetahuan Ibu Tentang Penggunaan Antipiretik Pada Balita di Posyandu Dusun Jebugan Tirtomulyo Kretek Bantul Bulan Februari 2025

DIRA DESRIAL
2025 · Thesis · Open Access

Antipyretics are drugs used to reduce body temperature due to fever or an increase in body temperature. Normal human body temperature is 36-37°C. Lack of knowledge of housewives about the use of antipyretics in toddlers greatly affects the use of antipyretics. The purpose of this study was to determine the level of knowledge of mothers about the use of antipyretics in toddlers at Posyandu Jebugan Tirtomulyo Kretek Bantul. This study used descriptive observational research methods. The research sample used saturated sampling technique as many as 58 mothers in the Jebugan Hamlet Posyandu Tirtomulyo Kretek Bantul who have toddlers aged 12-59 months. The instrument used in this study was a closed questionnaire. Data were collected and the results were then calculated in the form of % with the categories of good (76-100%), sufficient (56-75%), less (<56%). The results showed that the level of knowledge of mothers about the use of antipyretics in toddlers at the Posyandu Jebugan Hamlet Tirtomulyo Kretek Bantul, namely 28 respondents (48%) had a good level of knowledge, 25 respondents (43%) had a sufficient level of knowledge and 5 respondents (9%) had a lack of knowledge. The conclusion of this study is that most of the mothers' level of knowledge about the use of antipyretics in toddlers is in the good category.

Uji Sifat Fisik Sediaan Hand Sanitizer Minyak Atsiri Serai Wangi (Cymbopogon nardus L.)

NAJWA PUTY JELITA
2025 · Thesis · Open Access

Hand sanitizer gel is easy to use, absorbs well and gives a cold sensation. Natural ingredient of citronella essential oil contains antibacterial agents that can be used in hand sanitizers. Gelling agents are components that affect physical properties of the preparation. The purpose of the study was to determine the physical properties of citronella essential oil hand sanitizer. The research method uses experimental research with posttest only design. The active substances are citronella essential oil and gelling agent use carbopol with concentration variations 0.5%; 0.75%; and 1.0%. Statistical data analysis with one way ANOVA and LSD to determine the difference in gelling agent concentration variation in the preparation. The research results of the organoleptic and homogeneous tests descriptively with the results of FI white colored, citronella scent, slightly thick consistency, FII white colored, citronella scent, thick consistency, FIII white colored, citronella scent, very thick consistency. All three formulas have a homogeneous homogeneity. The pH test results were FI (6.34±0.20), FII (5.74±0.10), and FIII (5.07±0.14) had a significant difference (sig0.05). The results of the spread diameter were FI (6.71±0.14), FII (5.95±0.21), and FIII (5.22±0.09) had a significant difference (sig0.05). The conclusion of the study showed that the results of the physical properties test of citronella essential oil hand sanitizer, including organoleptic, homogeneity, pH, and spread diameter meet the requirements.

Pola Peresepan Asam Folat Pada Ibu Hamil Di Apotek Sultan Agung Yogyakarta Periode Januari - Juni 2024

MELLY WAHYU SETYOWATI
2025 · Thesis · Open Access

The prevalence of anemia in pregnant women based on SKI (2023) is 27.7%. During pregnancy, an additional 300 calories are needed, especially in the second and third trimesters. The daily requirement of folic acid in pregnant women is 600-800 micrograms, (Levine et al., 2018). The World Health Organization states that anemia is a serious global public health problem that specifically attacks women of childbearing age and pregnant women. The prevalence of anemia in pregnant women is 36.5%. The purpose of this study was to determine the pattern of folic acid prescription in pregnant women at the Sultan Agung Yogyakarta Pharmacy for the period January-June 2024. This study used a descriptive observational method and retrospective data collection with a purposive sampling method. The study population was 425 sheets and the sample used was 85 sheets. The data were analyzed by calculating the percentage of appropriate folic acid doses, inappropriate folic acid doses, the amount of single folic acid, and the amount of combination folic acid. This study has limitations set by the researcher on the inclusion and exclusion criteria with the final results being appropriate or inappropriate. The results of the study of folic acid prescribing patterns in pregnant women at Sultan Agung Pharmacy for the period January-June 2024 showed that the percentage of dose compliance (78%), the percentage of non-compliance (22.4%), the percentage of single folic acid (20%), and the percentage of combination folic acid (80%).

Pola Peresepan Obat Kortikosteroid Oral di Apotek Madukismo Farma Periode Mei-Agustus Periode Mei-Agustus 2024

SHAFIRA ARGA DEWI SURYA ANDYNI
2025 · Thesis · Open Access

Corticosteroids are drugs that contain steroid hormones that are useful for increasing steroid hormones in the body when needed, and relieving inflammation, as well as suppressing the overwork of the immune system. Based on a preliminary study conducted by researchers by taking 10 random prescriptions in January there were 4% prescriptions, in March there were 2% and in May there were 6% prescriptions containing corticosteroid drugs. The purpose of this study is to determine the pattern of prescribing oral corticosteroid drugs at Madukismo Farma Pharmacy for the May-August 2024 period. This study uses an observational method that is descriptive with retrospective data collection. with a total sample of 90 recipes. The results of the study found that regarding the pattern of prescribing oral corticosteroids based on gender and age, the most were female patients (56%) and 18-59 years old (80%). Meanwhile, the percentages based on the type of drug and the most drug class are methylprednisolone (78%) and glucocorticoid group (100%).

Gambaran Tingkat Pengetahuan Tentang DAGUSIBU Obat Tetes Mata Pada Siswa Kelas X SMK Negeri 1 Purwosari Gunungkidul Bulan Januari 2025

MITA PUSPITA SARI
2025 · Thesis · Open Access

ABSTRACT The eyes are the five senses of humans that play an important role in the process of daily activities, the eyes can experience visual disturbances that affect their quality. Lack of understanding about medicine can cause health problems. Therefore, it is important to apply DAGUSIBU (Get, Use, Store, Dispose) for the safe and effective use of eye drops. The purpose of this study was to determine the level of knowledge about DAGUSIBU eye drops among students of SMK Negeri 1 Purwosari Gunungkidul. This research method is descriptive observational with purposive sampling technique. Data collection used a questionnaire that had been tested for validity and reliability. The sample of this study amounted to 70 students. Data were collected and the results were then calculated as % to be categorized as good (≥76%-100%), sufficient (56% - 76%), and less (56%). After scoring, data were analyzed in descriptive form. The results showed that students who gained good knowledge about DAGUSIBU eye drops were 29 students (41%), 35 students (50%) and 6 students (9%). It can be concluded that the knowledge of students of SMK Negeri 1 Purwosari Gunungkidul regarding DAGUSIBU eye drops most students fall into the sufficient category.

TINGKAT PENGETAHUAN SANTRI KELAS XI & XII TENTANG PENGGUNAAN OBAT ANTASIDA DI PONDOK PESANTREN AL - ISLAM KOTA SERANG – BANTEN PADA BULAN JANUARI 2025

FAUZAN NATHOFANI ATAMIMI
2025 · Thesis · Open Access

Gastritis merupakan peradangan yang terjadi pada lapisan lambung disebabkan oleh faktor lain diantaranya tidak teraturnya pola makan, mengkonsumsi kopi, teh, alkohol. Angka kejadian gastritis pada beberapa daerah di Indonesia cukup tinggi dengan prevelensi 274.396 kasus dari 238.452.952 jiwa penduduk. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan santri kelas XI dan XII di Pondok Pesantren Al-Islam Kota Serang mengenai penggunaan obat antasida. Metode penelitian ini dilakukan secara observasional yang bersifat deskriptif dengan teknik simple random sampling. Sampel pada penelitian adalah santri pondok pesantren Al-Islam yang berjumlah 85 Responden. Alat yang digunakan lembar kuesioner yang terdiri dari 15 pertanyaan. Analisa data dilakukan secara deskriptif yaitu menghitung jawaban yang benar kemudian dihitung persentase tingkat pengetahuan dan dikategorikan berdasarkan baik, cukup, kurang. Hasil penelitian menunjukkan bahwasantri memiliki tingkat pengetahuan dalam kategori baik 28,2%, cukup 60%, dan 11,8% kurang. Hasil ini menunjukkan bahwa sebagian besar santri belum sepenuhnya memahami penggunaan antasida secara benar, terutama terkait efek samping dan aturan pakai. Kurangnya akses informasi serta minimnya edukasi kesehatan menjadi faktor yang mempengaruhi tingkat pengetahuan. Sehingga dapat disimpulkan bahwa tingkat pengetahuan santri tentang penggunaan obat antasida masuk dalam kategori cukup.

TINGKAT PENGETAHUAN PASIEN TERHADAP PENGGUNAAN OBAT ANTASIDA DOEN DALAM PENGOBATAN PENYAKIT GASTRITIS (MAAG) DI KLINIK PURUHITA HEALTH CENTER MAGELANG

APRILIA PUTRI NURAZIZAH
2025 · Thesis · Open Access

The prevalence of gastritis in Central Java reached 79.6%, in Magelang Regency, gastritis is a disease that occurs frequently in 2019-2021. The incidence of gastritis at the Puruhita Health Center Clinic increased from July to October 2024, this affects the use of DOEN antacid drugs which continues to increase. This study aims to determine the level of patient knowledge regarding the use of DOEN antacid drugs in the treatment of gastritis. This research method is observational and descriptive with a cross-sectional approach. The sample is patients diagnosed with gastritis and meets the inclusion criteria. The sampling method uses purposive sampling with a total of 66 respondents. Data analysis is in the form of quantitative data from the results of questionnaire answers. The results of the answers are then calculated using a formula and grouped based on the percentage of good, sufficient, and poor knowledge levels. The results of the study showed that the level of respondent knowledge regarding the use of DOEN Antacid drugs consisted of 2 categories, namely the good category of 54 respondents (81.8%) and the sufficient category of 12 respondents (18.2%). Factors that influence the level of knowledge of respondents include access to information and experience in treating diseases, so that a good level of knowledge will have an impact on the patient's clinical outcome, one of which is the achievement of the therapeutic effect of the drug. Thus, it can be concluded that the level of patient knowledge regarding the use of DOEN Antacid drugs is in the good category.

Evaluasi Penyimpanan Sediaan Obat di Apotek Kinanti Farma Kecamatan Imogiri Kabupaten Bantul Periode Januari - Februari 2024

DHEA WINA WARA RAHMAWATI
2025 · Thesis · Open Access

Pharmacy is a pharmaceutical service facility where pharmacists practice pharmacy. The purpose of storing drugs is to maintain the quality of pharmaceutical preparations, avoid irresponsible use, maintain availability, and facilitate searching and supervision. The purpose of this study was to find out about how to manage drug storage at Kinanti Farma Imogiri Pharmacy, Bantul Regency. This research method uses a descriptive observational method, the number of samples of 144 drug items was used. The sampling technique used Probability Sampling, namely Random Sampling. Evaluation of drug storage used in this study used Permenkes No. 73 of 2016. The results of the study showed that drug storage at the Kinanti Farma Pharmacy, Imogiri District, Bantul Regency, was in accordance with the Regulation of the Minister of Health No. 73 of 2016 concerning Pharmaceutical Standards in Pharmacies by 80%, which value is included in the "Good" storage criteria.

Gambaran Tingkat Pengetahuan Ibu-Ibu PKK Terhadap Diabetes Melitus di Kepek RT 06 Timbulharjo Sewon, Bantul

DEWI BERLIANA ROMAULI NAPITUPULU
2025 · Thesis · Open Access

Diabetes Melitus merupakan salah satu penyakit kronis yang tidak menular, memerlukan waktu yang lama dan proses penyembuhan dalam jangka panjang. Berdasarkan data dari International Diabetes Federation pada tahun 2021, terdapat 537 juta orang pada usia 20-79 tahun di dunia menderita diabetes melitus dengan angka prevelensi sebesar 10,5% dan akan terus bertambah pada tahun 2030 dengan perkiraan 643 juta jiwa. Hasil Riset Kesehatan Dasar tahun 2018 menunjukkan provinsi Daerah Istimewa Yogyakarta di urutan ketiga dengan 3,1% kasus. Tujuan penelitian ini untuk mengetahui gambaran tingkat pengetahuan ibu-ibu PKK terhadap diabetes melitus di Kepek RT 06 Timbulharjo Sewon Bantul Penelitian ini menggunakan metode observasional yang bersifat deskriptif. Teknik pengambilan data menggunakan metode purposive sampling. Analisa data dengan menggunakan kuesioner yang telah divalidasi dan kemudian diisi oleh responden yang menjadi sampel penelitian. Data yang diperoleh kemudian dihitung skor dari hasil kuesioner serta dilakukan analisa data. Jumlah responden dalam penelitian ini 60 responden. Hasil penelitian tentang gambaran tingkat pengetahuan ibu-ibu PKK terhadap diabetes melitus di Kepek RT 06 Timbulharjo Sewon Bantul, sebesar 13 responden (21,67%) memiliki pengetahuan baik, 41 responden (68,33%) berpengetahuan cukup, dan 6 responden (10%) berpengetahuan kurang, sehingga dapat disimpulkan bahwa tingkat pengetahuan ibu-ibu PKK terhadap diabetes melitus dapat dikategorikan cukup.

Review Artikel : Pengobatan Hipertensi Menggunakan Daun Kemangi (Ocimum basilicum)

DWI SETIAWAN
2025 · Thesis · Open Access

Hipertensi merupakan salah satu penyakit kardiovaskular yang paling umum dan paling banyak disandang masyarakat. Apabila hipertensi tidak ditangani dengan serius dapat menyebabkan komplikasi seperti penyakit jantung, stroke, gangguan fungsi ginjal bahkan kematian. Penggunaan obat hipertensi diperlukan alternatif lain yang efektif dan aman untuk dikonsumsi jangka panjang, seperti pengobatan herbal menggunakan daun kemangi. Penelitian ini bertujuan untuk mengetahui pemberian daun kemangi berdasarkan review artikel dapat digunakan sebagai antihipertensi. Metode yang digunakan adalah metode deskriptif kualitatif dengan pengumpulan data melalui observasi dan artikel primer dari penelitian yang dipublikasikan antara tahun 2019-2024, diunduh dari situs seperti Google Scholar, PubMed, dan Indonesia Onesearch. Data dianalisis menggunakan purposive sampling berdasarkan kriteria inklusi antara lain artikel membahas daun kemangi sebgai antihipertensi, keamanan, artikel berbahasa Indonesia dan Inggris, artikel full text, original artikel tahun 2019-2024, dengan menambahkan keyword daun kemangi, hipertensi, keamanan.

Gambaran Tingkat Pengetahuan Ibu Tentang Penanganan Demam Pada Balita di Dusun Murangan VII, Triharjo, Sleman

PUTRI FATYA CHAERANI
2025 · Thesis · Open Access

Demam terjadi pada keadaan atau suhu tubuh lebih dari normal mulai dari 37,5C. Demam pada anak dapat menyebabkan kejang, kerusakan otak, koma, gejala dari penyakit, bahkan demam bisa menyebabkan kematian. Kejadian ini terjadi pada rentang usia 1 bulan sampai 5 tahun. Berdasarkan WHO tahun 2020 jumlah kasus demam pada anak diseluruh dunia mencapai angka 17 juta. Tujuan pada penelitian ini adalah untuk mengetahui gambaran tingkat pengetahuan ibu tentang penanganan demam pada balita di Dusun Murangan VII Triharjo Sleman. Metode penelitian yang digunakan adalah observasional yang bersifat deskriptif. Metode pengambilan sampel yang digunakan dalam penelitian ini yaitu metode sampling jenuh atau sensus, dimana populasi akan dijadikan sampel semua. Penelitian ini menggunakan alat ukur berupa kuisoner tertutup untuk mengetahui tingkat pengetahuan responden. Data yang diperoleh dideskripsikan sebagai penegtahuan baik, cukup, kurang. Hasil penelitian menunjukkan bahwa tingkat pengetahuan ibu tentang penanganan demam di Dusun Murangan VII, Triharjo,Sleman yaitu 42 responden (52,5%) memiliki tingkat pengetahuan baik, 30 responden (37,5%) memiliki tingkat pengetahuan cukup dan 8 responden (10%) memiliki tingkat pengetahuan yang masih kurang. Kesimpulan dari penelitian ini mayoritas tingkat pengetahuan ibu tentang penanganan demam yaitu dalam kategori baik.

Hubungan Tingkat Pendidikan Terhadap Tingkat Pengetahuan Tentang Swamedikasi Diare Di Dusun Papungan Sleman Bulan Februari 2025

HANINTYA ADISTY NOVITAENGGI
2025 · Thesis · Open Access

Diare merupakan penyakit yang mengakibatkan kesakitan dan kematian. Data penemuan kasus diare tahun 2020 sebanyak 5.228 kasus dan tahun 2021 sebanyak 2.532 kasus. Jumlah kasus diare pada perempuan sebanyak 2167 kasus (54,85 %), jumlah penemuan kasus diare pada laki-laki sebanyak 1784 kasus (45,15 %). Pendidikan berhubungan dengan pengetahuan diare, semakin baik pengetahuan maka menjamin semakin tidak terkena diare. Penelitian ini bertujuan untuk mengetahui hubungan tingkat pendidikan terhadap tingkat pengetahuan tentang swamedikasi diare di dusun Papungan Sleman. Penelitian ini menggunakan metode observasional analitik dengan pendekatan cross sectional. Pengambilan sampel menggunakan Teknik stratified random sampling. Sampel pada penelitian ini yaitu warga dusun Papungan Sleman sejumlah 96 responden. Data diperoleh dengan menyebar kuesioner kepada responden kemudian dianalisis menggunakan SPSS dengan uji statistik chi-square. Penelitian ini menunjukkan hasil bahwa diperoleh uji korelasi chi-square 0,018 menunjukkan adanya hubungan tingkat pendidikan terhadap pengetahuan tentang swamedikasi diare di Dusun Papungan Sleman. Pengetahuan masyarakat Papungan Sleman mengenai swamedikasi diare masuk dalam kategori baik 43 responden (45%).

Tingkat Pengetahuan Masyarakat Tentang Penggunaan Obat Dalam Swamedikasi Di Dusun Pulegundes 1 Gunungkidul Januari 2025

DZAKY RYAN FERDIANSYAH
2025 · Thesis · Open Access

Badan Pusat Statistik noted that in 2023 there were 79.74% of the Indonesian population and 73.3% in the Yogyakarta area who carried out self-medication, this shows that self-medication is often carried out in society. One of the main factors that influences someone in carrying out self-medication is knowledge. A person's knowledge about health will have an impact on their own behavior towards disease. The purpose of this study was to determine the level of public knowledge about the use of drugs in self-medication in the Pulegundes 1 hamlet, Gunungkidul in January 2025. The research method used is descriptive observational research. The sampling method used in this study is the purposive sampling method, from a population of 727 people, a sample of 90 respondents was taken. This study uses a measuring instrument in the form of a closed questionnaire to determine the level of knowledge of respondents. The data obtained are described as good, sufficient, and lacking knowledge. The results of the study showed that the level of public knowledge in Dusun Pulegundes 1 Gunungkidul 56.66% was classified as good, 36.66% was classified as sufficient, 6.66% was classified as lacking. The conclusion of this study is that the level of public knowledge in Dusun Pulegundes 1 Gunungkidul about the use of drugs in self-medication is mostly in the good category at 56.66%.

Gambaran Tingkat Pengetahuan Masyarakat tentang Penggunaan Vitamin C di Dusun Kaligayam Temon Kulon Progo Bulan Januari 2025

SEPTIANA NANDA PUTRI
2025 · Thesis · Open Access

Kesadaran mengkonsumsi vitamin C erat kaitannya dengan faktor mengenai tingkat pengetahuan tiap individu itu sendiri. Vitamin C merupakan zat yang sangat dibutuhkan oleh tubuh karena berfungsi sebagai agen antimikroba yang dapat melawan mikroorganisme penyebab infeksi dan membantu meningkatkan serta mempertahankan imunitas tubuh. Kekurangan vitamin C dapat menyebabkan terganggunya sistem kekebalan tubuh yang menyebabkan tubuh lebih mudah terpapar penyakit. Tujuan dilakukan penelitian ini yaitu untuk mengetahui gambaran tingkat pengetahuan masyarakat tentang penggunaan vitamin C di Dusun Kaligayam, Temon, Kulon Progo. Metode yang digunakan dalam penelitian ini yaitu metode observasional deskriptif. Teknik pengambilan data dilakukan dengan purposive sampling pada 91 responden. Pengambilan data dilakukan dengan menggunakan kuisioner tertutup yang dibuat oleh peneliti sendiri dan mengadopsi kuisioner dari penelitian Santika & Dhirisma (2024). Hasil penelitian yang diperoleh mengenai tingkat pengetahuan penggunaan vitamin C di Dusun Kaligayam memiliki tingkat pengetahuan baik sebanyak 76 responden (83,5%). Pengetahuan cukup sebanyak 15 responden (16,5%) dan tidak terdapat responden dengan kriteria kurang. Dari hasil penelitian, dapat disimpulkan bahwa tingkat pengetahuan masyarakat di Dusun Kaligayam, Temon, Kulon Progo masuk dalam rentang kriteria baik.

Pengaruh Perbedaan Metode Ekstraksi Terhadap Rendemen dan Kandungan Kimia Ekstrak Daun Katuk (Sauropus androgynus)

TITA RATRI
2024 · Thesis · Open Access

Katuk leaves contain chemical compounds such as alkaloids, tannins, flavonoids, saponins and steroids. Extraction of a plant can affect the yield and chemical content. The purpose of this study was to determine the effect of different extraction methods on the yield and chemical content of katuk leaf extract. This research method uses Post-test Only Design and the extraction used is maceration and soxhlet, with 96% ethanol solvent. 50 g of simplisia powder was macerated with solvent in a ratio of 1:10 for 3x24 hours. Soxhlet extraction is carried out until the liquid is no longer colored. The filtrate obtained was evaporated and air dried until a thick extract was obtained. The extracts obtained from each extraction method were calculated for yield and chemical content. The yield was calculated statistically with the Shapiro-Wilk normality test. If the data is normal and homogeneous , the Independent Sample T-Test test is continued, if the data is not normal and not homogeneous, the Mann-Whitney test is continued. While the chemical content is descriptive.

Tingkat Pengetahuan Ibu tentang Penggunaan Obat Cacing di Puskesmas Umbulharjo II Yogyakarta

SHELLA SEPTIANA
2024 · Thesis · Open Access

Helminthiasis is caused by poor hygiene and sanitation, non-adherence to deworming treatment, and lack of knowledge about worm infections. Cases of helminthiasis infection in Yogyakarta Special Region (DIY) in 2015 reached 182 cases and in 2016 reached 165 cases. This study took place at Umbulharjo II Community Health Center in Yogyakarta. The purpose of this study was to determine the level of maternal knowledge about the use of deworming drugs at Puskesmas Umbulharjo II Yogyakarta. This study is a descriptive type of observational research. Prospective data collection with sampling using purposive sampling method. Data were collected using a questionnaire instrument and analyzed by calculating the percentage value of correct answers to filling out the questionnaire then the level of knowledge was categorized as good, sufficient, lacking. The number of samples used in this study was 90 people.

Tingkat Pengetahuan Pasien Terhadap Penanganan Diare Pada Anak di Apotek Kaliurang Sedayu Bulan Februari - Maret 2024

MEININA PUTRI PRATIWI
2024 · Thesis · Open Access

Diarrhea is one of the infectious diseases of the digestive tract which is a health problem in the world including Indonesia. The incidence of diarrhea increased by about 2 billion incidence of diarrhea and 1.9 million resulted in deaths in children under five worldwide. The prevalence rate of childhood diarrhea in Indonesia was recorded as 18,665 (9%) children aged 0-11 months, 18,333 (15%) children aged 12-23 months, 19. 112 (12.8%) children aged 24-35 months, 18,821 (10.2%) children aged 36-47 months and as many as 18,688 (8%) children aged 48-59 months.The purpose of this study was to determine the level of parental knowledge of the treatment of diarrhea in children at Kaliurang Sedayu Pharmacy. This study used descriptive observational method. This study used quantitative data to determine the level of parental knowledge on the treatment of diarrhea in children at Kaliurang Sedayu Pharmacy. Data analysis used a Guttman scale where the correct answer was given a score of 1 and the wrong answer was given a score of 0.

Pengaruh Jenis Pelarut Terhadap Rendemen dan Kandungan Kimia Ekstrak Daun Katuk (Sauropus androgynus)

TRI UTAMI REJEKI
2024 · Thesis · Open Access

Katuk leaves contain chemical compounds such as alkaloids, tannins, flavonoids, saponins, triterpenoids, polyphenols, steroids, quinones, monoterpenoids and sesquiterpenoids. Factors that influence the yield and chemical content of katuk leaf extract are differences in the type of solvent. The aim of this research was to determine the effect of the type of extraction solvent on the yield value and chemical content of katuk leaf extract. The extraction method used in this research was maceration, using 96% ethanol and n-hexane as solvents. Simplicia powder is macerated with each solvent (ratio 1:3) for 3 x 24 hours with stirring 15 minutes every 24 hours. The maceration results obtained were then filtered and air dried until a thick extract was obtained, then the yield value and chemical content of the katuk leaf extract were tested. Data from the results were analyzed using SPSS with the Shapiro Wilk normality test and Levene's homogeneity test with a confidence level of 95%. The yield value data was then subjected to an Independent Sample T-test to determine the influence between groups of solvent types.

Uji Viskositas dan Diameter Sebar Sediaan Gel Sari Buah Strawberry (Fragaria x ananssa Duch.) dengan Basis CMC Na

CHRISTY NATALIA LIMBU DATU
2024 · Thesis · Open Access

Strawberry is a fruit that contains antioxidant compounds that are effective for maintaining skin health and preventing premature aging. To facilitate its application, strawberry juice is formulated in gel form. The gel is formulated with CMC Na (Carboxymethyl cellulose Sodium) base. CMC Na has good attachment strength to the skin and can also increase the viscosity of gel preparations. This study aims to determine the effect of the addition of strawberry juice on the viscosity and diameter of spread of CMC Na-based gel preparations. This study was conducted using an experimental method, namely post testonly control group design by making the preparation formula, namely gel formula without strawberry juice (F1) and gel formula with strawberry juice (F2). Gel is made by developing CMC Na in water heated at a temperature of 80°C until it forms like a gel, then covered with aluminium and left to stand for 24 hours.The gel was allowed to stand for 24 hours so that the gel preparation could expand properly. The preparation was evaluated by viscosity and diameter spread test. Data that were normally distributed were analysed using the Independent t-test and data that were not normally distributed were tested with the Mann withney test with 95% confidence level.

Pengaruh Konsentrasi Sari Buah Jambu Biji Merah (Psidium guajava Linn.) Terhadap Nilai pH Sediaan Lip Balm

RIFKA AMELIA
2024 · Thesis · Open Access

Lip balm merupakan pelembab bibir yang dikemas dalam bentuk semi padat. Salah satu bahan alami yang dapat digunakan untuk pembuatan sediaan lip balm yaitu buah jambu biji merah karena kandungan vitamin C yang tinggi. Derajat keasaman (pH) merupakan parameter penting dalam produk kosmetik yang dapat mempengaruhi tingkat daya penyerapan pada kulit. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi sari buah jambu biji merah terhadap nilai pH sediaan lip balm. Jenis penelitian ini adalah eksperimental dengan metode posttest only control grup design. Formula lip balm terdiri dari formula kontrol basis dan formula dengan sari buah jambu biji merah 2,5% (FI), 5% (FII) dan 7,5% (FIII). Sediaan lip balm yang masing- masing telah di uji pH menggunakan pH meter digital. Analisis data penelitian dilakukan menggunakan program SPSS 23. Uji normalitas dilakukan dengan Shapiro-Wilk dan uji homogenitas dilakukan dengan Levene’s Test. Jika data yang dihasilkan, yaitu data terdistribusi normal dan homogen dilanjutkan dengan uji One Way Anova. Jika nilai yaitu P0,05 maka dilanjutkan dengan Uji LSD. Namun jika data tidak terdistribusi normal dilakukan uji non parametrik dengan Kruskall Wallis.